Expert Answer
- Comment
OINTMENTS ARE SEMISOLID DOSAGE FORMS INTENDED FOR EXTERNAL APPLICATION TO SKIN OR MUCOUS MEMBRANE .
2 TYPES
MEDICATED :EITHER DISSOLVED OR DISPERSED IN A VEHICLE AS FINE POWDER e.g STEROIDS
NON MEDICATED : UNMEDICATED OINTMENTS ARE USED FOR PHYSICAL .EXAMPLE :PROTECTANTS or LUBRICANTS.OINTMENT BASES
OINTMENT BASES ARE CLASSIFIED INTO FOUR GENERAL GROUPS.
OLEAGINOUS BASES.
ABSORPTION BASES.
WATER-REMOVABLE
WATER SOLUBLE BASESSELECTION OF APPROPRIATE BASE
DEPENDS UPON PURPOSE FOR WHICH OINTNENT IS GOING TO BE APPLIED
DESIRED RELEASE OF DRUG
SUBSTANCE FROM OINTMENT BASE
DESIRABILITY OF TOPICAL ABSORPTIONMETHOD OF PREPARATION
2 TYPES
1) INCORPORATION
2) FUSIONPRESERVATION
BY ADDING ANTIMICROBIALS LIKE
METHYLPARABEN
PROPYLPARABENPACKAGING
OINTMENTS SHOULD BE PACKAGED SO THAT THERE ARE NO AIR SPACES IN JAR MUST BE STORED IN WELL CLOSED CONTAINER TO AVOID CONTAMINATION.STORAGE
STORE AT COOL PLACE TO AVOID SOFTENING AND LIQUIFICATION OF BASE.LABELLING
IT SHOULD BE LABELLED AS:
“FOR EXTERNAL USE ONLY”
ليست هناك تعليقات:
إرسال تعليق