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  1.Decreased total protein may indicate.-Abnormal loss of protein from the digestive tract or the inability of the digestive tract to absorb proteins (protein-losing enteropathy)

  • Kidney disorder called nephrotic syndrome
  • Scarring of the liver and poor liver function (cirrhosis)

  Increased alpha-1 globulin proteins may be due to:

  • Acute inflammatory disease
  • Cancer
  • Chronic inflammatory disease (for example, rheumatoid arthritis, SLE)

  Decreased alpha-1 globulin proteins may be a sign of:

  • Alpha-1 antitrypsin deficiency

  Increased alpha-2 globulin proteins may indicate a:

  • Acute inflammation
  • Chronic inflammation

  (2)Decreased alpha-2 globulin proteins may indicate:

  • Breakdown of red blood cells (hemolysis)

  Increased beta globulin proteins may indicate:

  • A disorder in which the body has problems breaking down fats (for example, hyperlipoproteinemia, familial hypercholesterolemia)
  • Estrogen therapy

  Decreased beta globulin proteins may indicate:

  • Abnormally low level of LDL cholesterol
  • Malnutrition

  Increased gamma globulin proteins may indicate:

  • Blood cancers, including multiple myeloma, Waldenström macroglobulinemia, lymphomas, and chronic lymphocytic leukemias
  • Chronic inflammatory disease (for example, rheumatoid arthritis)
  • Acute infection
  • Chronic liver disease

  (3) Some of the most common routine tests are:

  • complete blood count (CBC)
  • chemistry (basic metabolic) panel
  • thyroid panel
  • nutrient tests for levels of vital nutrients, such as iron or B vitamins

  Some other tests that you may want include:-enzyme markers if you’re at risk for cancer or other conditions like liver cirrhosis, stroke, or celiac disease

  • sexually transmitted disease (STD) tests if you have multiple sexual partners or a new partner